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 Dr. Argelia Lorence
Assistant Professor of Metabolic Engineering
BS - Biochemical Engineering, Universidad Autónoma
Metropolitana - Iztapalapa
MS - Biotechnology, Instituto
de Biotecnologia Universidad Nacional Autónoma
de México
Ph.D. - Biotechnology, Instituto de
Biotecnologia Universidad Nacional Autónoma
de México
Post-doctoral - Plant
metabolic engineering, Texas A&M and Virginia Tech
Office: ABI 310
Phone: 1.870.680.4322
Email:
alorence@astate.edu
In August of 2005 I joined the
Arkansas Biosciences Institute as a Tenure-Track
Assistant Professor in Metabolic Engineering. I
have a joint appointment with the Department of
Chemistry and Physics. My research group focuses in
the development of metabolic engineering strategies
to enhance nutritional, medicinal, environmental and
agronomical traits in plants. Our current models of
research are: the mouse-ear cress (Arabidopsis
thaliana), tobacco (Nicotiana tobacum),
rice (Oryza sativa), and the rain of gold (Galphimia
glauca). A list of projects currently developed
in my group is as follows:
-Study of the role of vitamin C in
the control of aging and reproductive activity in
plants.
- Study and manipulation of the vitamin C
metabolic network in Arabidopsis thaliana
(collaboration with Drs. Craig Nessler and Boris Chevone,Virginia Tech, Blacksburg, VA).
- Metabolite profiling of the
vitamin C metabolic network in plants (collaboration
with Dr. Robyn Hannigan, ASU-Chemistry and Physics).
- Survey of the vitamin C foliar
content of plants of the mustard family growing in
the State of Arkansas (collaboration with Dr. Staria
Vanderpool, ASU-Biological Sciences).
- Metabolic engineering of
phytoalexins produced by tobacco and Hyoscyamus
muticus hairy root cultures (collaboration with
Dr. Fabricio Medina-Bolivar, ASU-ABI).
- Metabolic engineering of
triterpenes with sedative properties produced by
Galphimia glauca cell and hairy roots cultures
[collaboration with Drs. María Luisa Villarreal (CEIB-UAEM,
Cuernavaca, México), and Rogelio Pereda-Miranda (Facultad
de Química-UNAM, Mexico City, México)].
- Metabolic engineering for the
enhancement of nutritional and agronomical traits of
rice varieties (collaboration with Dr. Gregory
Phillips, ASU-Agriculture, and Dr. Hellen Miller,
USDA-Stuttgart, AR).
- Metabolite profiling of plant
extracts as fingerprints for forensic applications.
- Molecular speciation of selected
Mexican medicinal plant species (collaboration with
Dr. Rachel Mata, Facultad de Química-UNAM, Mexico
City, México).
- Mechanisms of toxicity and
remediation strategies of Superfund environmental
toxicans [collaboration with PIs working at
University of Arkansas for Medical Sciences (UAMS,
Little Rock, AR), University of Arkansas (UAF,
Fayetteville, AR), the National Center for
Toxicological Research (NCTR-FDA, Jefferson, AR),
and Arkansas State University (ASU, Jonesboro, AR)].
- Harnessing the potential
of plant genomics for the detection and remediation
of explosives and chemical weapons (collaboration
with Dr. Robyn Hannigan, ASU-Chemistry and Physics).
- Extensive teaching (First Year
Experience, Advanced Biochemistry, and Special
Topics) and mentoring activities (undergraduate and
graduate students).
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